Tannic Acid

Product Name:

Tannic acid

Synonyms:

Tannic acid, AR;Tannic acid 1401-55-4 Gallotannin;TANNIC ACID PWD;Gallotannic acid 1401-55-4 Tannic acid;Tannic acid Source: Chinese natural gall nuts;Tannic acid tested according to Ph.Eur.;Tannic acid Vetec(TM) reagent grade;Tannic Acid(Pharmaceutical/Tech/Dyes/Food Grade)

CAS:

1401-55-4

MF:

C76H52O46

MW:

1701.2

EINECS:

215-753-2

Product Categories:

Inhibitors;Catechins & Tannins;Plant Extract;Food additive and acidulant

Mol File:

1401-55-4.mol

Melting point 

218 °C(lit.)

Boiling point 

862.78°C (rough estimate)

density 

1.2965 (rough estimate)

FEMA 

3042 | TANNIC ACID (QUERCUS SPP.)

refractive index 

1.7040 (estimate)

Fp 

198°C

storage temp. 

Storage temperature: no restrictions.

solubility 

ethanol: soluble100mg/mL, yellow to brown

form 

Powder/Solid

color 

Yellow to light brown

PH

3.5 (100g/l, H2O, 20°C)

Water Solubility 

250 g/L (20 ºC)

Sensitive 

Air & Light Sensitive

Merck 

14,9052

BRN 

8186396

Stability:

Stable. Incompatible with metallic salts, strong oxidizing agents, iron and other heavy metals.

InChIKey

LRBQNJMCXXYXIU-PPKXGCFTSA-N

EPA Substance Registry System

Tannic acid (1401-55-4)

Hazard Codes 

Xi,Xn

Risk Statements 

40-62-63-68-36/37/38-52/53

Safety Statements 

24/25-36-26-36/37/39-22-61

WGK Germany 

2

RTECS 

WW5075000

Autoignition Temperature

980 °F

TSCA 

Yes

HS Code 

32019090

Hazardous Substances Data

1401-55-4(Hazardous Substances Data)

Toxicity

LD50 oral in rabbit: 5gm/kg

Production method

Tannin is presented in the bark and fruit of a variety of trees (such as oak and sumac) and is also the main component of the gall formed when the trees are also subject to attack by insects with the content being 50-70%. Crush the gallic, remove the dead insects and insect droppings and other impurities, put into the copper or wood extraction tank and extract with soft water; the extract was concentrated under reduced pressure, add a small amount of ether, apply spray drying so that the light tannin is obtained. Medicinal tannic acid is produced through extracting the concentrated solution with ether with the extract being bleached by sodium bisulfite and further recovery of ether to obtain the final medicine tannin. 
Crush the Gallic, screen, and then impregnate with water, put the immersed water for clarification and preheating, and then spray-drying with refined powder sieved to obtain the final products. 
Throw 100 kg of refined naphthalene into the sulfonated kettle, heat to 125 ℃, add 120 kg of concentrated sulfuric acid under stirring and have reaction at 155~165 ℃ for 6~8h. Apply sampling and determine the end point, if it is completely soluble in water, the sulfonation completes. Gradually cool to 110 ℃, dilute with a small amount of water. At about 80 ℃, the material liquid was compressed into the condensation tank. At about 70 ℃, add drop wise of 39 kg of 37% aqueous solution of formaldehyde, and after completion of the dropping, have reaction at 80~90 ℃ for 3 h to obtain the black viscous liquid which is the finished product.
The larch bark is crushed, extracted, purified, concentrated and dried to obtain the finished product.

Category

toxic substances

Toxicity grading

highly toxic

Acute toxicity

intraperitoneal-mouse LD50: 150 mg/kg; intravenous-mouse LD50: 50 mg/kg

Flammability and hazard properties

thermal decomposition yields acrid smoke

Storage characteristics

warehouse: low-temperature, dry and ventilated

Extinguishing media

Water, carbon dioxide, foam, powder

Chemical Properties

Tannic acid, C14H10O9, also known as digallic acid, tannin, and gallotannin, is a yellowish powder that decomposes at 210°C (410°F). Tannic acid is derived from nutgalls. It is soluble in water and alcohol,and is insoluble in acetone and ether. Tannic acid is used in tanning,textiles, and as an alcohol denaturant. An amorphous form of tannic acid, also known as pentadigalloylglucose, exists with the formula C76H52O46. It is a yellowish to brownish powder that is very soluble in alcohol and ether.It also decomposes between 210 and 215°C (410 and 419 °F). This form is used to clarify wine or beer, as a reagent,and as a mordant in dyeing.

Chemical Properties

Quebracho, an evergreen tree 15 to 18 m (49 to 59 ft) tall, grows abundantly throughout South America (Argentina, in particular). The Argentine variety is characterized by its bright-red bark, rich in tannin, used for dyeing. The part used is the bark (from either the trunk or branches). Quebracho is tonic, aromatic.

Chemical Properties

Tannic acid or hydrolysable gallotannin is a complex polyphenolic organic structure that yields gallic acid and either glucose or quinic acid as hydrolysis products. Tannic acid is odorless or has a faint, characteristic odor and an astringent taste.

Uses

Tannic Acid is a sequestrant that refers to a mixture of hydrolyzable tannins of a more complex structure than gallic acid. it is used in clarifying beer and wine. see tannins.

Uses

nonspecific enzyme/receptor blocker

Uses

Clarifying agent; pH control

Definition

ChEBI: A gallotannin obtained by acylation of the five hydroxy groups of D-glucose by 3,4-dihydroxy-5-[(3,4,5-trihydroxybenzoyl)oxy]benzoic acid (a gallic acid dimer).

Definition

tannic acid: A yellowish complexorganic compound present in certainplants. It is used in dyeing as a mordant.

Preparation

Tannic acid is obtained by solvent extraction from the nutgalls or the excrescences that form on the young twigs of Quercus olivier and allied species of Quercus L.; from the seed pods of Tara (Caesalpinia spinosa); or from the nutgalls of various sumac species, including Rhus semialata, R. coriaria, R. glabra and R. typhia.

Health Hazard

Inhalation causes irritation of nose and throat, coughing, and sneezing. Ingestion may cause gastric disturbance. Contact with eyes causes irritation.

Fire Hazard

Special Hazards of Combustion Products: Decomposes at 210° to carbon dioxide and pyrogallol, which can form irritating vapors.

Safety Profile

Poison by intravenous and intraperitoneal routes. Questionable carcinogen with experimental tumorigenic data. When heated to decomposition it emits acrid smoke and irritating fumes.

Preparation Products

DOWEX(R) 1X8-->Gallic acid-->3,4,5-Trimethoxybenzaldehyde-->CHILLIORANGE-->Propyl gallate-->Methyl 3,4,5-trimethoxybenzoate-->D-glucose pentakis[3,4-dihydroxy-5-[(trihydroxy-3,4,5-benzoyl)oxy]benzoate]-->synthetic tanning agent No.28-->TANNASE-->synthetic tanning agent DLT-10-->Acorn shell btown-->tannalbin-->SODIUM TANNATE-->long-acting vasopressinl-->Gallic acid trimethyl ether-->Sulfonated sodium tannin-->tremella polysaccharide

Raw materials

Sodium bisulfite-->Naphthalene-->formaldehyde