Product Name: |
ETHYL OLEATE |
CAS: |
111-62-6 |
MF: |
C20H38O2 |
MW: |
310.51 |
EINECS: |
203-889-5 |
Mol File: |
111-62-6.mol |
|
Melting point |
−32 °C(lit.) |
Boiling point |
216-218 °C15 mm Hg |
density |
0.87 g/mL at 25 °C(lit.) |
FEMA |
2450 | ETHYL OLEATE |
refractive index |
n20/D 1.451(lit.) |
Fp |
>230 °F |
storage temp. |
−20°C |
solubility |
chloroform: soluble10% |
form |
Oily Liquid |
color |
Clear |
Sensitive |
Light Sensitive |
JECFA Number |
345 |
Merck |
14,6828 |
BRN |
1727318 |
InChIKey |
LVGKNOAMLMIIKO-VAWYXSNFSA-N |
CAS DataBase Reference |
111-62-6(CAS DataBase Reference) |
NIST Chemistry Reference |
9-Octadecenoic acid (Z)-, ethyl ester(111-62-6) |
EPA Substance Registry System |
Ethyl oleate (111-62-6) |
Safety Statements |
23-24/25-22 |
WGK Germany |
2 |
RTECS |
RG3715000 |
F |
10-23 |
TSCA |
Yes |
HS Code |
29161900 |
Overview |
Ethyl oleate is a colourless liquid that is normally formed by condensing
ethanol and oleic acid. Notably, the compound is normally produced by the
body during intoxication of ethanol. Its other names are 9-Octadecenoic acid
(Z)-, Ethyl cis-9-octadecenoate, (Z)-9-Octadecenoic acid ethyl ester, and
Oleic acid, ethyl ester. The compound contributed to approximately 17% of the
total fatty acids esterified to phosphatidylcholine in porcine platelets.
Ethyl oleate is neutral and is a more lipid-soluble form of oleic acid. |
Uses |
Pharmaceutical Industry |
Description |
Ethyl oleate is a fatty acid ester formed by the condensation of oleic
acid and ethanol. It is a colorless to light yellow liquid. Ethyl oleate is
produced by the body during ethanol intoxication. |
Chemical Properties |
Ethyl oleate has a faint, floral note. |
Chemical Properties |
clear pale yellow oily liquid |
Chemical Properties |
Ethyl oleate occurs as a pale yellow to almost colorless,
mobile, oily liquid with a taste resembling that of olive oil and a slight,
but not rancid odor. |
Occurrence |
Reported found in cocoa, buckwheat, elderberry and babaco fruit (Carica pentagona Heilborn). |
Uses |
Ethyl oleate is a flavoring and fragrance agent. |
Uses |
It was obtained by the hydrolysis of various animal and vegetable fats and oils. |
Uses |
Usually used to prepare the oily phase of self-microemulsifying drug delivery system (SMEDDS) for tacrolimus (Tac). |
Production Methods |
Ethyl oleate is prepared by the reaction of ethanol with oleoyl chloride in the presence of a suitable hydrogen chloride acceptor. |
Definition |
ChEBI: A long-chain fatty acid ethyl ester resulting from the formal condensation of the carboxy group of oleic acid with the hydroxy group of ethanol. |
Preparation |
By direct esterification of oleic acid with ethyl alcohol in the presence of HCl at the boil; in the presence of Twitchell’s reagent or chlorosulfonic acid. |
Preparation Products |
Oleyl alcohol-->coconut oil alcohol acylamide |
Raw materials |
Etanol-->Calcium chloride-->cis-9-Octadecenoic acid |