Product Description

Diphenyl oxide Basic information

Product Name:	Diphenyl oxide
CAS:	101-84-8
MF:	C12H10O
MW:	170.21
EINECS:	202-981-2
Mol File:	101-84-8.mol

Diphenyl oxide Chemical Properties

Melting point	26 °C
Boiling point	259 °C(lit.)
density	1.073 g/mL at 25 °C(lit.)
vapor density	>5.86 (25 °C, vs air)
vapor pressure	<1 mm Hg ( 20 °C)
FEMA	3667 \| DIPHENYL ETHER
refractive index	n20/D 1.579(lit.)
Fp	>230 °F
storage temp.	2-8°C
solubility	alcohol: soluble(lit.)
Specific Gravity	1.073
Relative polarity	2.8
Odor	Weak geranium.
Odor Threshold	0.1ppm
explosive limit	0.8-1.5%(V)
Water Solubility	insoluble
FreezingPoint	27℃
Merck	14,7288
JECFA Number	1255
BRN	1364620
Henry's Law Constant	2.13 at 20 °C (approximate - calculated from water solubility and vapor pressure)
Exposure limits	NIOSH REL: TWA 1 ppm (7 mg/m3), IDLH 100 ppm; OSHA PEL: TWA 1 ppm; ACGIH TLV: TWA 0.1, STEL 2 ppm (adopted).
InChIKey	USIUVYZYUHIAEV-UHFFFAOYSA-N
CAS DataBase Reference	101-84-8(CAS DataBase Reference)
NIST Chemistry Reference	Diphenyl ether(101-84-8)
EPA Substance Registry System	Phenyl ether (101-84-8)

Diphenyl oxide Safety Information

Hazard Codes	N,Xi,T
Risk Statements	51/53-36/37/38-39/23/24/25-23/24/25-36/38-36
Safety Statements	60-61-57-37/39-26-45-36/37
RIDADR	UN 3077 9/PG 3
WGK Germany	2
RTECS	KN8970000
Autoignition Temperature	610 °C
TSCA	Yes
HS Code	2909 30 10
HazardClass	9
PackingGroup	III
Hazardous Substances Data	101-84-8(Hazardous Substances Data)
Toxicity	LD50 orally in Rabbit: 2450 mg/kg LD50 dermal Rabbit > 7940 mg/kg

Diphenyl oxide Usage And Synthesis

Chemical Properties	Diphenyl oxide is a practically colorless crystalline solid with a strong geranium-like odor. clear pale yellowish liquid after melting. It is almost completely insoluble in water, but dissolves in most of the common organic solvents. Its high thermal stability at temperatures as high as 350 to 400°C. together with its noncorrosiveness and general chemical inertness make it eminently suitable as a component of high-boiling heat transfer media.
Chemical Properties	Diphenyl Ether has not been observed in nature. It is a colorless liquid or a crystalline solid (mp 26.8°C) with an odor reminiscent of geranium leaves. Diphenyl ether is obtained as a by-product in the production of phenol by high-pressure hydrolysis of chlorobenzene. Because of its stability and low price, diphenyl ether is used in large quantities in soap perfumes.
Chemical Properties	Diphenyl ether has a harsh, floral-green, metallic geranium-type odor.
Physical properties	Colorless solid or liquid with a geranium-like odor. An experimentally determined odor threshold concentration of 100 ppbv was reported by Leonardos et al. (1969).
Definition	ChEBI: An aromatic ether in which the oxygen is attached to two phenyl substituents. It has been found in muscat grapes and vanilla.
Preparation	By heating potassium phenolate with bromobenzene or with chlorobenzene at elevated temperatures.
Aroma threshold values	Aroma characteristics at 1.0%: grassy, musty, powdery, dry, terpy, ocimenelike, aromatic and hoplike with green juniper berry nuances.
Taste threshold values	Taste characteristics at 10 ppm: dry chemical, floral rosey with carrot, tropical and hoplike terpy notes and a green vegetative and woody nuance.
General Description	Colorless liquid with a mild pleasant odor. May float or sink in water. Freezing point is 81°F.
Air & Water Reactions	Insoluble in water.
Reactivity Profile	Diphenyl oxide can react with oxidizing materials. . A vigorous reaction occurred between the ether and chlorosulfuric acid.
Health Hazard	Inhalation may cause nausea because of disagreeable odor. Contact of liquid with eyes causes mild irritation. Prolonged exposure of skin to liquid causes reddening and irritation. Ingestion produces nausea.
Fire Hazard	Diphenyl oxide is combustible.
Chemical Reactivity	Reactivity with Water No reaction; Reactivity with Common Materials: No reaction; Stability During Transport: Stable; Neutralizing Agents for Acids and Caustics: Not pertinent; Polymerization: Not pertinent; Inhibitor of Polymerization: Not pertinent.
Safety Profile	Moderately toxic by ingestion. Prolonged exposure damages liver, spleen, kidneys, and thyroid, and upsets gastrointestinal tract. A skin and eye irritant. Combustible when exposed to heat or flame; can react with oxidizing materials. For explosion hazard, see ETHERS. To fight fire, use water, foam, CO2, dry chemical. When heated to decomposition it emits acrid smoke and irritating fumes
Purification Methods	Crystallise the ether from 90% EtOH. Melt it, wash it with 3M NaOH and water, dry it with CaCl2 and fractionally distil it under reduced pressure. Fractionally recrystallise it from its melt and store over P2O5. [Beilstein 6 IV 562.]